রবিবার, ৩১ মার্চ, ২০১৩

Giant panda artificially inseminated at U.S. National Zoo

WASHINGTON (Reuters) - Veterinarians at the National Zoo artificially inseminated the zoo's female giant panda Mei Xiang on Saturday after natural breeding failed to occur, zoo keepers said.

Mei Xiang was put under general anesthesia and inseminated with a combination of fresh semen and frozen semen collected from the zoo's male giant panda Tian Tian. The scientists said they planned a second insemination later on Saturday.

Veterinarians detected a rise in hormone levels on Tuesday, indicating Mei Xiang was ready to breed but said "no competent breeding" between the panda pair had occurred.

"We are hopeful that our breeding efforts will be successful this year, and we're encouraged by all the behaviors and hormonal data we've seen so far," said Dave Wildt, head of the Center for Species Survival at the Smithsonian Conservation Biology Institute.

Scientists will continue to monitor Mei Xiang's hormone levels in the coming months and conduct ultrasounds to determine whether she is pregnant. A pregnancy lasts between 95 and 160 days, they said.

Mei Xiang has given birth to two cubs. One died a week after its birth last year. The other was born in 2005 and is now at the China Conservation and Research Center for the Giant Panda in Wolong.

(Reporting by Jane Sutton; editing by Jackie Frank)

Source: http://news.yahoo.com/giant-panda-artificially-inseminated-u-national-zoo-173415545.html

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Astronaut Celebrates Easter in Space (Easter Eggs, Included)

Children around the world aren't the only ones having an Easter egg hunt today. Astronauts in space will get Easter treats, too.

Canadian astronaut Chris Hadfield, who commands the International Space Station, made sure that the Easter Bunny would make a special trip to the orbital lab today (March 31) just in time for an Easter celebration in space.

"Good Morning, Earth! A fine Easter Sunday morning to you from the crew of the International Space Station," Hadfield wrote in a post on Twitter, where he is chronicling his mission under the name @Cmdr_Hadfield.

Hadfield snapped a sunrise photo of Earth on Easter showing the sun glinting off the Great Lakes in North America this morning to mark the occasion. Then he revealed his Easter secret.

"Don't tell my crew, but I brought them Easter Eggs :)," Hadfield wrote as he posted a photo of his space Easter treats. [Astronaut Chris Hadfield's Amazing Space Photos]

In the photo, six large plastic Easter eggs ? each a different color ?float inside a plastic bag while Hadfield presses a finger to his lips in a "Shh" gesture.

Easter Sunday is a day off for the space station crew because it falls on a weekend. Hadfield is Canada's first commander of the station and took charge of the orbiting laboratory earlier in March.

Hadfield's Expedition 35 crew includes himself, two Americans and three Russians. Three crewmembers, American astronaut Chris Cassidy and Russian cosmonauts Pavel Vinogradov and Alexander Misurkin, just arrived at the station on Thursday (March 28).

Astronauts in space have a long tradition of spending holidays in space dating back decades to the early days of human spaceflight, when NASA astronauts celebrated Christmas orbiting the moon during the 1968 Apollo 8 mission.

Christmas, Thanksgiving, New Year's Day and other traditional holidays from Russia and other space station partner countries have been celebrated in space since the first crew took up residence in the orbiting laboratory in 2000. The space station has been manned by rotating crews ever since.

Hadfield has shown a dedication to marking holidays off the planet. In March, he donned a green shirt and bowtie for St. Patrick's Day, and in February he wore a heart headband for Valentine's Day and a funny hat and necklace for Mardi Gras.

Hadfield and two Expedition 35 crewmates ? NASA astronaut Tom Marshburn and Russian cosmonaut Roman Romanenko ? are due to return to Earth in May. They have been living on the space station in since mid-December.

Email Tariq Malik at tmalik@space.com or follow him @tariqjmalikand Google+. Follow us @Spacedotcom, Facebookand Google+. Original article on SPACE.com.

Copyright 2013 SPACE.com, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/astronaut-celebrates-easter-space-easter-eggs-included-151008296.html

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Artificial spleen to treat bloodstream infections: Sepsis therapeutic device under development

Mar. 30, 2013 ? The Wyss Institute for Biologically Inspired Engineering at Harvard University announced today that it was awarded a $9.25 million contract from the Defense Advanced Research Projects Agency (DARPA) to further advance a blood-cleansing technology developed at the Institute with prior DARPA support, and help accelerate its translation to humans as a new type of sepsis therapy.

The device will be used to treat bloodstream infections that are the leading cause of death in critically ill patients and soldiers injured in combat.

To rapidly cleanse the blood of pathogens, the patient's blood is mixed with magnetic nanobeads coated with a genetically engineered version of a human blood 'opsonin' protein that binds to a wide variety of bacteria, fungi, viruses, parasites, and toxins. It is then flowed through microchannels in the device where magnetic forces pull out the bead-bound pathogens without removing human blood cells, proteins, fluids, or electrolytes -- much like a human spleen does. The cleansed blood then flows back to the patient.

"In just a few years we have been able to develop a suite of new technologies, and to integrate them to create a powerful new device that could potentially transform the way we treat sepsis," said Wyss founding director and project leader, Don Ingber, M.D., Ph.D. "The continued support from DARPA enables us to advance our device manufacturing capabilities and to obtain validation in large animal models, which is precisely what is required to enable this technology to be moved towards testing in humans."

The team will work to develop manufacturing and integration strategies for its core pathogen-binding opsonin and Spleen-on-a-Chip fluidic separation technologies, as well as a novel coating technology called "SLIPS," which is a super-hydrophobic coating inspired from the slippery surface of a pitcher plant that repels nearly any material it contacts. By coating the inner surface of the channels of the device with SLIPS, blood cleansing can be carried out without the need for anticoagulants to prevent blood clotting.

In addition to Ingber, the multidisciplinary team behind this effort includes Wyss core faculty and Harvard School of Engineering and Applied Science faculty member Joanna Aizenberg, Ph.D., who developed the SLIPS technology; Wyss senior staff member Michael Super, Ph.D., who engineered the human opsonin protein; and Mark Puder, M.D., Ph.D., Associate Professor of Pediatric Surgery at Boston Children's Hospital and Harvard Medical School who will be assisting with animal studies.

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/biochemistry/~3/O8CKu3xNkz0/130330130531.htm

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শনিবার, ৩০ মার্চ, ২০১৩

93% The Sapphires

All Critics (101) | Top Critics (20) | Fresh (94) | Rotten (7)

Let's trivialize a legacy of cruelty and denigration, in a country where indigenous people suffered from centuries of human rights abuse! And let's make the carnage of Vietnam look like a paintball game!

[A] genial, entertaining, clich?-ridden showbiz story from Australia.

"The Sapphires" illustrates how the same old story - in this case, the one about a 1960s girl group and its struggles - can be freshened up through the novelties of place and characterization.

A very conventional story of a '60s Australian girl group gains extra power from its context and setting in this fact-based story set to the beat of Motown soul.

The performers improve it, or save it, depending on your viewpoint.

"The Sapphires" is a bit like a puppy you're trying to house break. It may have its bad cinematic moments but it's just so darn appealing that you have to love it.

A rousing soundtrack helps to compensate for some of the historical embellishments in this Australian crowd-pleaser.

'Sapphires' got heart and soul

It might not possess the exuberant innocent fun of 'That Thing You Do!' or the overall brilliance of 'The Commitments' but 'The Sapphires' shines enough in its own right. (Complete Content Details for Parents also available)

If you love the music of Motown and enjoy a feel good success flick, then "The Sapphires" fits the bill.

Delirious surprises crowd out the clich?s in this thoroughly disarming movie.

Mauboy has one hell of a voice, and the Sapphires' vocal performances speak to the endless power of great soul songs.

Irresistibly feel good, sound good movie, wears hearts and social relevance on its sparkly sleeve. . .Fun and racial tolerance amidst war [with] sterling aborigine talent.

The most affable, innocuous outing ever set in a war zone.

With O'Dowd in the lead, and a hit-soundtrack-ready selection of tunes from the Stax and Motown catalogs and more, The Sapphires is popcorn entertainment, with some earned laughs and a genuine heart.

It helps that the leading actors are so skillful and appealing, beginning with Chris O'Dowd as a roguish Irishman who becomes the girls' manager...

You've seen this type of tale many times before...but the inspired-by-a-true-story Aboriginal slant adds interest, the actresses create unique characters and Chris O'Dowd really shines.

This familiar but supremely well-told and produced tale of the unlikely rise of an Aboriginal female pop group in the Vietnam War-era is feel-good entertainment at its best. Performances, solid script and great music all hit the high notes.

It sidesteps the usual cliches. Fame and fortune matter less than the human connections that are fostered and repaired on this unlikely journey.

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Source: http://www.rottentomatoes.com/m/the_sapphires_2012/

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Rogue Dentist May Have Exposed 7,000 Patients to HIV, Hepatitis

The Tulsa Health Department is warning 7,000 patients of a local dentist's office that they could have contracted HIV, hepatitis B or hepatitis C from poor sterilization practices.

Dr. Wayne Harrington, an oral surgeon with a practice in Tulsa, Okla., is being investigated by the state dental board, the state bureau of narcotics and the federal Drug Enforcement Agency because one of his patients recently tested positive for hepatitis C and HIV without known risk factors other than receiving dental treatment.

Upon hearing of the infected patient, the Oklahoma Board of Dentistry conducted a surprise inspection of Harrington's practice on March 18, allegedly finding numerous problems, including regular use of a rusty set of instruments on patients with known infections, and the practice of pouring bleach on wounds until they "turned white."

Calls to Harrington's office were directed to an operator, who told ABC News the clinic no longer took voicemails. The operator said patients were being referred to another clinic, but did not disclose the clinic's name.

Susan Rogers, executive director of Oklahoma's Board of Dentistry, called the incident a "perfect storm." On top of his many violations in sanitary practice, the dentist was a Medicaid provider, which means he had a high proportion of patients with HIV or hepatitis, she said.

Harrington and his staff told investigators that he treated a "high population of known infectious disease carrier patients," according to a complaint filed by the Oklahoma Board of Dentistry.

He allegedly allowed unlicensed dental assistants to administer medication, according to the complaint. These assistants were left to decide which medications to administer, and how much was appropriate.

Drug cabinets were unlocked and unsupervised during the day, and Harrington did not keep an inventory log of drugs, some of which were controlled substances. One drug vial expired in 1993.

"During the inspections, Dr. Harrington referred to his staff regarding all sterilization and drug procedures in his office," the complaint read. "He advised, 'They take care of that. I don't.'"

Harrington allegedly re-used needles, contaminating drugs with potentially harmful bacteria and trace amounts of other drugs, according to the complaint. Although patient-specific drug records indicated that they were using morphine in 2012, no morphine had been ordered since 2009.

The instruments for infected patients was given an extra dip in bleach in addition to normal cleaning methods, but they had red-brown rust spots, indicating that they were "porous and cannot be properly sterilized," according to the complaint.

The Tulsa Health Department said Harrington's patients will receive letters by mail notifying them of the risk and steps to obtain free-of-charge testing.

While 7,000 patients may have been exposed, Joseph Perz, an epidemiologist with the U.S. Centers for Disease Control and Prevention, said it's "extremely rare" to see dental transmission of HIV and hepatitis B or C. In July 2012, 8,000 Coloradans were notified that their dentist had reused needles, potentially exposing them to the blood-borne viruses. But not a single case was identified, according to the CDC.

Dental transmission is not impossible, however. Perz cited a dental fair three years ago in which hepatitis B was transmitted between patients.

In July 2012, more than 1,800 veterans who received dental care at a St. Louis VA Medical Center were warned that improper cleaning of dental tools may have exposed them to HIV and hepatitis.

The Tulsa Health Department has set up a hotline at (918) 595-4500 for people with questions.

ABC News' Dr. Richard Besser and Katie Moisse contributed to this story.

Also Read

Source: http://news.yahoo.com/rogue-dentist-may-exposed-7-000-patients-hiv-234810996.html

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Solar Impulse to fly across the US, pilots preparing for a trip around the world in 2015

Solar Impulse to fly across the US in preparation for a trip around the world in 2015

We've been tracking the sun-powered plane known as Solar Impulse for years as it roved hither and yon. Today, Solar Impulse's pilots, Bertrand Piccard and Andre Borschberg, came to NASA's Ames research center to announce their plan to fly across America. The cross-country tour will begin in the Bay Area and end in New York, with stops in Phoenix, Dallas and Washington DC in between. Solar Impulse will also land in either Atlanta, Nashville or St. Louis, with the plane and its pilots set to stay in each locale for about a week to ten days to talk about the project before moving on. For the next month, Piccard and Borschberg will perform test flights around the Bay Area in preparation, and the plan is for the journey to start on May 1st, with an estimated arrival in Gotham sometime in early July.

The point of this new flight is to inspire and educate the public in general of the benefits of renewable energy and efficiency, and to encourage school children and university students in particular to "think off the grid" and innovate and invent on their own. To that end, the pilots will be broadcasting live transmissions and allowing the public to speak with them as they fly, in addition to providing access to flight planning information on the Solar Impulse website. Read on to learn a bit more about the Solar Impulse project and it's future plans.

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Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/57fVZc9ok_w/

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শুক্রবার, ২৯ মার্চ, ২০১৩

Exclusive: Wal-Mart may get customers to deliver packages to online buyers

By Alistair Barr and Jessica Wohl

SAN FRANCISCO (Reuters) - Wal-Mart Stores Inc is considering a radical plan to have store customers deliver packages to online buyers, a new twist on speedier delivery services that the company hopes will enable it to better compete with Amazon.com Inc.

Tapping customers to deliver goods would put the world's largest retailer squarely in middle of a new phenomenon sometimes known as "crowd-sourcing," or the "sharing economy."

A plethora of start-ups now help people make money by renting out a spare room, a car, or even a cocktail dress, and Wal-Mart would in effect be inviting people to rent out space in their vehicle and their willingness to deliver packages to others.

Such an effort would, however, face numerous legal, regulatory and privacy obstacles, and Wal-Mart executives said it was at an early planning stage.

Wal-Mart is making a big push to ship online orders directly from stores, hoping to cut transportation costs and gain an edge over Amazon and other online retailers, which have no physical store locations. Wal-Mart does this at 25 stores currently, but plans to double that to 50 this year and could expand the program to hundreds of stores in the future.

Wal-Mart currently uses carriers like FedEx Corp for delivery from stores - or, in the case of a same-day delivery service called Walmart To Go that is being tested in five metro areas, its own delivery trucks.

"I see a path to where this is crowd-sourced," Joel Anderson, chief executive of Walmart.com in the United States, said in a recent interview with Reuters.

Wal-Mart has millions of customers visiting its stores each week. Some of these shoppers could tell the retailer where they live and sign up to drop off packages for online customers who live on their route back home, Anderson explained.

Wal-Mart would offer a discount on the customers' shopping bill, effectively covering the cost of their gas in return for the delivery of packages, he added.

"This is at the brain-storming stage, but it's possible in a year or two," said Jeff McAllister, senior vice president of Walmart U.S. innovations.

Indeed, the likelihood of this being broadly adopted across the company's network of more than 4,000 stores in the United States is low, according to Matt Nemer, a retail analyst at Wells Fargo Securities.

"I'm sure it will be a test in some stores," he added. "But they may only keep it for metro markets and for higher-priced items."

LEGAL BOUNDARIES

Start-ups such as TaskRabbit and Fiverr already let individuals rent out their time and expertise to companies and people looking for small jobs to be completed.

Zipments was founded in 2010 as a crowd-sourced delivery network that allowed anyone over 18 years old with a vehicle, a text-enabled phone, and a PayPal account to bid on courier services for local businesses.

Such online match-making businesses often push legal boundaries - and a Wal-Mart crowd-sourced delivery program would be no different, according to Nemer.

Online packages delivered by customers may never reach their destination, either through theft or fraud, the analyst said.

Such a crowd-sourced delivery service may not be as reliable as FedEx or United Parcel Service, which have insured drivers, he added.

"You are comfortable with a FedEx or UPS truck in your driveway, but what about a stranger knocking on your door?" Nemer said.

ZIPMENTS EVOLVES

While Zipments started out with a pure crowd-sourcing approach, the company now does more screening of drivers before allowing them to be part of its delivery network, Chief Executive and co-Founder Garrick Pohl said in an interview. It now serves big cities including New York and Chicago.

Theft, fraud and late deliveries have never been a problem, but insurance and licenses were an obstacle, Pohl explained.

Drivers often need personal liability insurance to cover package delivery activities. Cargo insurance is also needed. Zipments self-insures this risk up to $250, but the firm encourages its couriers to buy additional coverage for higher-value packages, Pohl said.

In some areas, like downtown Chicago, people also need a courier license to deliver things, he added.

"Zipments now helps people get all these things set up before allowing them to deliver goods," Pohl said.

Still, he said the issues are not insurmountable, citing pizza restaurants, which have used part-time drivers to deliver pies for years.

"It's a great solution for large retailers like Wal-Mart," Pohl said. "We'd like to see them move quicker, but it's great that they are considering it."

Zipments is trying to provide such services to retailers, although Pohl declined to say which companies the start-up is talking to about this.

(Reporting by Alistair Barr and Jessica Wohl; Editing by Jonathan Weber, Martin Howell and Leslie Gevirtz)

Source: http://news.yahoo.com/exclusive-wal-mart-may-customers-deliver-packages-online-050124872--sector.html

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Eyeballs found in KC gas station trash not human

KANSAS CITY, Mo. (AP) ? Police say a pair of eyeballs found in a medical box in a Kansas City gas station's trash bin aren't human.

Police spokesman Steve Young said Thursday that the police lab examined the eyeballs and determined they likely came from a pig.

Young says a worker at a Conoco gas station in northern Kanas City called police after finding the cardboard box late Wednesday. The box was labeled, "Keep refrigerated."

Surveillance video shows two men in a blue Toyota leaving the package on the trash bin.

Young says police aren't investigating further because no crime appears to have been committed. Earlier, police had said that no eye banks or hospitals in the area were awaiting delivery of any eyeballs.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/aa9398e6757a46fa93ed5dea7bd3729e/Article_2013-03-28-Eyes%20Found/id-dd5fe4aa30774ac3a5365ba5afbf49cf

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2013 ACMG Foundation/Signature Genomic, PerkinElmer Inc., Travel Award Winner announced

2013 ACMG Foundation/Signature Genomic, PerkinElmer Inc., Travel Award Winner announced [ Back to EurekAlert! ] Public release date: 28-Mar-2013
[ | E-mail | Share Share ]

Contact: Kathy Ridgely Beal
kbeal@acmg.net
301-238-4582
American College of Medical Genetics

Caleb P. Bupp, M.D., was honored as the 2013 recipient of the ACMG Foundation/Signature Genomics from PerkinElmer, Inc. Travel Award at the American College of Medical Genetics and Genomics 2013 Annual Clinical Genetics Meeting in Phoenix, AZ

Caleb P. Bupp MD was honored as the 2013 recipient of the ACMG Foundation/Signature Genomics from PerkinElmer, Inc. Travel Award at the American College of Medical Genetics and Genomics (ACMG) 2013 Annual Clinical Genetics Meeting in Phoenix, AZ.

Dr. Bupp was selected to receive the award for his platform presentation, "Twenty years of neural tube defect surveillance and prevention in South Carolina."

Dr. Bupp completed his MD degree at the University of Toledo College of Medicine. He completed his residency in Pediatrics at the University of Louisville and is currently completing his Medical Genetics Residency at the Greenwood Genetics Center.. Dr. Bupp received his Bachelor of Science in Molecular Biology and graduated Magna Cum Laude from Grove City College. He is currently a Medical Consultant for the U.S. Department of Justice.

The ACMG Foundation/Signature Genomics Travel Award is given to a trainee ACMG member whose abstract submission was chosen as a platform presentation during the ACMG Annual Clinical Genetics Meeting. The ACMG program committee selects the Travel Award recipient based on scientific merit. In recognition of the selected presentation, Signature Genomics covers the travel costs for the recipient to the ACMG meeting.

"The Foundation for Genetic and Genomic Medicine is grateful to Signature Genomics' for its continued generous support of the development of medical genetic researchers through this Travel Award," said Bruce R. Korf, MD, PhD FACMG, president of the ACMG Foundation for Genetic and Genomic Medicine.

"Signature Genomics is pleased to support the recognition of young researchers like Dr. Bupp who are working in the field of medical genetics and genomics. This presentation is just one of the many outstanding presentations at this year's ACMG meeting," said Beth Torchia, PhD, FACMG, Technical Laboratory Director at Signature Genomics.

###

About the ACMG and ACMG Foundation

Founded in 1991, the American College of Medical Genetics and Genomics (http://www.acmg.net) advances the practice of medical genetics and genomics by providing education, resources and a voice for more than 1600 biochemical, clinical, cytogenetic, medical and molecular geneticists, genetic counselors and other healthcare professionals committed to the practice of medical genetics. ACMG's activities include the development of laboratory and practice standards and guidelines, advocating for quality genetic services in healthcare and in public health, and promoting the development of methods to diagnose, treat and prevent genetic disease. Genetics in Medicine, published monthly, is the official ACMG peer-reviewed journal. ACMG's website offers a variety of resources including Policy Statements, Practice Guidelines, Educational Resources, and a Find a Geneticist tool. The educational and public health programs of the American College of Medical Genetics are dependent upon charitable gifts from corporations, foundations, and individuals. The ACMG Foundation for Genetic and Genomic Medicine, a 501(c)(3) nonprofit organization, is a community of supporters and contributors who understand the importance of medical genetics and genomics and genetic counseling in healthcare. Established in 1992, the ACMG Foundation supports the American College of Medical Genetics and Genomics' mission to "translate genes into health" by raising funds to promote the profession of medical genetics and genomics to medical students, to fund the training of future medical geneticists, to support best-practices and tools for practicing physicians and laboratory directors, to promote awareness and understanding of our work in the general public, and much more.

Note to editors: To arrange interviews with experts in medical genetics, contact Kathy Beal, MBA, ACMG Director of Public Relations at kbeal@acmg.net or 301-238-4582.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


2013 ACMG Foundation/Signature Genomic, PerkinElmer Inc., Travel Award Winner announced [ Back to EurekAlert! ] Public release date: 28-Mar-2013
[ | E-mail | Share Share ]

Contact: Kathy Ridgely Beal
kbeal@acmg.net
301-238-4582
American College of Medical Genetics

Caleb P. Bupp, M.D., was honored as the 2013 recipient of the ACMG Foundation/Signature Genomics from PerkinElmer, Inc. Travel Award at the American College of Medical Genetics and Genomics 2013 Annual Clinical Genetics Meeting in Phoenix, AZ

Caleb P. Bupp MD was honored as the 2013 recipient of the ACMG Foundation/Signature Genomics from PerkinElmer, Inc. Travel Award at the American College of Medical Genetics and Genomics (ACMG) 2013 Annual Clinical Genetics Meeting in Phoenix, AZ.

Dr. Bupp was selected to receive the award for his platform presentation, "Twenty years of neural tube defect surveillance and prevention in South Carolina."

Dr. Bupp completed his MD degree at the University of Toledo College of Medicine. He completed his residency in Pediatrics at the University of Louisville and is currently completing his Medical Genetics Residency at the Greenwood Genetics Center.. Dr. Bupp received his Bachelor of Science in Molecular Biology and graduated Magna Cum Laude from Grove City College. He is currently a Medical Consultant for the U.S. Department of Justice.

The ACMG Foundation/Signature Genomics Travel Award is given to a trainee ACMG member whose abstract submission was chosen as a platform presentation during the ACMG Annual Clinical Genetics Meeting. The ACMG program committee selects the Travel Award recipient based on scientific merit. In recognition of the selected presentation, Signature Genomics covers the travel costs for the recipient to the ACMG meeting.

"The Foundation for Genetic and Genomic Medicine is grateful to Signature Genomics' for its continued generous support of the development of medical genetic researchers through this Travel Award," said Bruce R. Korf, MD, PhD FACMG, president of the ACMG Foundation for Genetic and Genomic Medicine.

"Signature Genomics is pleased to support the recognition of young researchers like Dr. Bupp who are working in the field of medical genetics and genomics. This presentation is just one of the many outstanding presentations at this year's ACMG meeting," said Beth Torchia, PhD, FACMG, Technical Laboratory Director at Signature Genomics.

###

About the ACMG and ACMG Foundation

Founded in 1991, the American College of Medical Genetics and Genomics (http://www.acmg.net) advances the practice of medical genetics and genomics by providing education, resources and a voice for more than 1600 biochemical, clinical, cytogenetic, medical and molecular geneticists, genetic counselors and other healthcare professionals committed to the practice of medical genetics. ACMG's activities include the development of laboratory and practice standards and guidelines, advocating for quality genetic services in healthcare and in public health, and promoting the development of methods to diagnose, treat and prevent genetic disease. Genetics in Medicine, published monthly, is the official ACMG peer-reviewed journal. ACMG's website offers a variety of resources including Policy Statements, Practice Guidelines, Educational Resources, and a Find a Geneticist tool. The educational and public health programs of the American College of Medical Genetics are dependent upon charitable gifts from corporations, foundations, and individuals. The ACMG Foundation for Genetic and Genomic Medicine, a 501(c)(3) nonprofit organization, is a community of supporters and contributors who understand the importance of medical genetics and genomics and genetic counseling in healthcare. Established in 1992, the ACMG Foundation supports the American College of Medical Genetics and Genomics' mission to "translate genes into health" by raising funds to promote the profession of medical genetics and genomics to medical students, to fund the training of future medical geneticists, to support best-practices and tools for practicing physicians and laboratory directors, to promote awareness and understanding of our work in the general public, and much more.

Note to editors: To arrange interviews with experts in medical genetics, contact Kathy Beal, MBA, ACMG Director of Public Relations at kbeal@acmg.net or 301-238-4582.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-03/acom-2af032713.php

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UK-Odd Summary

Restaurant meals for kids fail nutrition test - U.S. consumer group

WASHINGTON (Reuters) - The menus offered to children by most U.S. restaurant chains have too many calories, too much salt or fat, and often not a hint of vegetables or fruit, according to a study by the Center for Science in the Public Interest. The group, which has agitated for everything from healthier popcorn at the movies to calorie labelling in supermarkets, found that among almost 3,500 combinations surveyed, kids' meals failed to meet nutritional standards 97 percent of the time.

Pennsylvania stadium aims to please fans with urinal video games

(Reuters) - Play doesn't need to stop for sports fans taking a bathroom break at a Pennsylvania minor-league baseball stadium that has installed video games in men's room urinals. The "hands-free" video game is played by directing oneself right or left in the urinals at the Lehigh Valley IronPigs' Coca-Cola Park in Allentown, Pennsylvania. The game is aimed at increasing prostate health awareness.

Going, going, gone - dodo bone up for sale in London

LONDON (Reuters) - A rare four-inch fragment of a dodo bone will go on sale in Britain in April, around 300 years after the flightless bird and icon of obsolescence was hunted to extinction. Auctioneers Christie's said on Wednesday it was hoping to raise as much as 15,000 pounds ($22,600) for the piece of a bird's femur.

New York cop who toured with band charged with disability fraud

NEW YORK (Reuters) - A New York police officer was charged on Tuesday with mail fraud for allegedly claiming disability benefits for two years while at the same time performing and touring with his heavy metal band, "Cousin Sleaze," according to court documents. Christopher Inserra, an officer with the Port Authority of New York and New Jersey, was the lead singer with the Brooklyn band, whose "Sick Maniacs" album features such songs as "Infection" and "Walk of Shame," according to an affidavit filed in U.S. District Court in Brooklyn.

Battle rages over bones of England's Richard III

LONDON (Reuters) - King Richard III is at the centre of a new fight over the location of his final resting place, just weeks after the remains of the last English king to die in battle were found underneath a council car park. Archaeologists announced one of the most remarkable finds in recent English history last month when they confirmed the discovery of the body of Richard, who was slain at the Battle of Bosworth Field in 1485, during excavations in Leicester.

"Shameful" sexist Ford car ads spark outrage in India

MUMBAI (Reuters) - A series of car ads, including one showing women bound and gagged in the trunk of a Ford driven by former Italian Prime Minister Silvio Berlusconi, has prompted Internet outrage in India and prompted an apology from Ford India. The ads came just days after India approved a tougher new law to punish sex crimes, following the fatal gang rape of a student in December. That attack sparked unprecedented protests over the treatment of women in the country.

"Panda-monium" as giant pandas arrive in Canada from China

TORONTO (Reuters) - Canada got a taste of international panda diplomacy on Monday with the arrival of two "Very Important Pandas" at the start of a 10-year loan to two Canadian zoos. Speaking as the two giant pandas arrived in Toronto from China, Chinese Ambassador Zhang Junsai - who gave the animals the VIP designation - noted that when he started his posting in Canada two years ago, he was greeted only by the Canadian director of protocol.

Punxsutawney Phil charged with fraud for early spring forecast

CLEVELAND (Reuters) - With a snow storm expected to batter the Plains, Midwest and East Coast this weekend, a spring-deprived Ohio prosecutor is taking out his frustration with the long winter on a famous prognosticating groundhog. "I decided it was about time we indicted Punxsutawney Phil afor fraud," said Mike Gmoser, prosecutor in Ohio's Butler County, in an interview Friday.

Harvard stripped of quiz tournament titles

CAMBRIDGE, Massachusetts (Reuters) - Harvard University will be stripped of four national quiz championship titles after organizers found a competitor from the Ivy League school inappropriately accessed information about questions used in the tournament. The National Academic Quiz Tournaments said that a security review found that Harvard competitor Andy Watkins accessed pages on its administrative Website just before the 2009, 2010 and 2011 Intercollegiate Championship Tournaments or "Quiz Bowls".

100,000 Portuguese sign petition to keep ex-PM Socrates off TV

LISBON (Reuters) - Portuguese state television channel RTP's plan to give former premier Jose Socrates a weekly commentary spot has sparked outrage, with 100,000 people signing a petition citing his "bad management" that led the country to take a bailout in 2011. "We, citizens and tax-payers, declare that we reject the presence of former Prime Minister Jose Socrates on any programme at RTP, television paid for by public funds of taxpayers suffering from the bad management of this gentleman," the Internet petition said.

Source: http://news.yahoo.com/uk-odd-summary-102513320.html

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বৃহস্পতিবার, ২৮ মার্চ, ২০১৩

Google Play Movies & TV adds in-content 'Info Card' search

Google Play Movies & TV

Update brings Google Play Moves & TV to India as well!

Google has just updated its Play Movies & TV app to include what it calls "Info Card" search, giving you information about the movie you're watching when you pause. Similar to what Amazon offers on its Kindle Fire tablets, Info Cards give you contextual information about the movie when you pause it, listing the actors in the scene, related movies and the soundtrack playing at the time. The cards are of course in the new "Google Now" card style, overlaid on the movie along the right side and look like what you'd get if you performed a Google search on the actor from a device.

Info Cards are available for only certain movies -- and certainly a limited selection -- that have an Info Cards "badge" on them, so be on the lookout next time you're renting or buying something from Google Play. Also included in this update is Play Movies & TV content for India, which is again a huge deal.



Source: http://feedproxy.google.com/~r/androidcentral/~3/7ePsdbpjsBY/story01.htm

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Court could sidestep gay marriage

Sen. Kirsten Gillibrand (D-NY) talks with Edith Windsor (R) in the hallway before a news conference on gay marriage.??

On Wednesday, the Supreme Court justices will hear arguments in the second gay marriage case ever in the court's history, again raising hopes from both sides that the court will weigh in decisively on the issue. On Tuesday, justices hinted that they may dodge a decision in California's gay marriage case, which makes the stakes even higher in this second case.

The case is Windsor v. United States, a challenge to the federal 1996 Defense of Marriage Act, which prohibits the federal government from recognizing same-sex marriages even in the nine states and District of Columbia that allow them. Eighty-three-year-old New Yorker Edith Windsor brought the suit after she was made to pay more than $363,000 in estate taxes when her same-sex spouse died, because the federal government did not recognize their marriage.

Windsor married her partner of more than four decades, Thea Spyer, in 2007 in Canada. Four years later, New York state legalized gay marriage.

Windsor argues that the law, commonly referred to as DOMA, unfairly excluded her marriage in more than 1,000 federal statutes in which marriage is relevant, including key parts of the tax code. She says the government has no legitimate reason to exclude same-sex married couples from benefits and obligations received by opposite-sex couples, and that she and other gay couples are being denied equal protection under the law.

The Obama administration has declined to defend DOMA, so the House of Representatives appointed seasoned attorney Paul Clement, who has argued before the Supreme Court many times, to take up the case. Clement will most likely argue that the federal government is not intruding on states' definition of marriage, but simply using its own definition in regard to federal benefits. He also has argued in legal briefs that the federal government has an interest in defining marriage as only between opposite sex couples because it encourages them to form stable family relationships when they procreate.

On Tuesday, some justices?including key swing vote Anthony Kennedy?expressed skepticism that the supporters of California's Proposition 8 have the legal authority to defend the law after the state's attorney general decided to drop the case. The DOMA case also is dogged by procedural issues, and it's possible the justices may throw it out without issuing a decision, letting the lower court's opinion stand. The Supreme Court has appointed a private lawyer to argue on Wednesday that the House of Representatives does not have standing in the case, signaling that the justices have real concerns about the standing issue.

It's possible that justices could dodge decisions in both Proposition 8 and DOMA, which would most likely be disappointing for proponents of both sides. If the DOMA case is thrown out, the federal government would most likely have to pay Windsor back her taxes, but the federal law would still remain in place. If the justices decide to dismiss Proposition 8, gay marriage will most likely become legal in California but not in other states.

But if the justices decide the House does have standing to appeal on behalf of DOMA, some legal experts have argued that the liberal justices may attract support from conservative justices to strike down the law by appealing to a states' rights argument. Marriage traditionally has been regulated by the states, the argument goes, and DOMA is unfairly interfering with New York and the eight other states that allow gay marriage.

Erwin Chemerinsky, the founding dean of University of California at Irvine Law School, said that based on the Proposition 8 oral argument, he was skeptical of that. "I think Justices Scalia and Alito clearly indicated the they're hostile to the marriage equality opinion," Chemerinsky said. "Thomas is likely to be with them."

If the conservative justices attract Kennedy, who has written two major opinions upholding gay rights, then DOMA would be affirmed as law. That would deal a blow to the gay rights movement strategy of getting gay marriage passed state-by-state, since the federal government would not be required to recognize those marriages. It's also possible that the court could use DOMA as a vehicle to declare that gay people have a right to marriage, though most legal experts say that's unlikely. The Proposition 8 case was seen as the better bet for gay marriage supporters to get a broad decision out of the justices, since the DOMA case is more narrowly focused on one aspect of a federal law.

?

Source: http://news.yahoo.com/blogs/ticket/justices-could-dodge-gay-marriage-decision-doma-case-090419542--politics.html

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The T-Mobile iPhone is Here at Last (Updating)

We knew it was coming sometime this year, and yesterday we heard murmurs that "sometime" could be today, and at last, it is. T-Mobile has an iPhone 5. Yes, it's the same iPhone 5 that was announced five months ago, but maybe (just maybe) it's better. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/MkbI5ChvBZg/the-t+mobile-iphone-is-here-at-last-updating

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North Korea reportedly cuts 3G for tourists, restricts access to long term visitors

It was just a month ago that North Korea started allowing mobile internet access to visitors (while still restricting it from citizens), but now a tour group says that program has ended. First reported by North Korea Tech, a post on the Koryo Group site indicates that tourists can still purchase SIM cards for international calling, but internet access is not available, a return to its policy from January. A recent blog post from the 22nd goes into more detail, explaining that 3G Koryolink access for foreigners "has been restricted to long term visitors/residents of Pyongyang only." With no word from the government on the policy change you'll have to insert your own reasoning, although we imagine Eric Schmidt is not pleased.

[Image credit: Jean Lee, Instagram]

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Comments

Via: TechCrunch, North Korea Tech, Tech in Asia

Source: Koryo Group (1), (2)

Source: http://www.engadget.com/2013/03/26/north-korea-3g-tourists-cut/

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বুধবার, ২৭ মার্চ, ২০১৩

Hot Wheels: BMW unveils new diesel 3-Series sedan

This photo provided by BMW shows the new BMW 3 Series Gran Turismo, one of two important variations of its popular 3-Series small luxury sports sedans. On Wednesday, March 27, 2013, the German automaker will formally unveil the new 3 Series Gran Turismo, which has a bigger distance between the front and rear wheels to create more rear-seat legroom and cargo space in the trunk. The company also will unveil the 328d in the U.S., a 3-Series equipped with a diesel engine that could get more than 40 miles per gallon on the highway. (AP Photo/BMW)

This photo provided by BMW shows the new BMW 3 Series Gran Turismo, one of two important variations of its popular 3-Series small luxury sports sedans. On Wednesday, March 27, 2013, the German automaker will formally unveil the new 3 Series Gran Turismo, which has a bigger distance between the front and rear wheels to create more rear-seat legroom and cargo space in the trunk. The company also will unveil the 328d in the U.S., a 3-Series equipped with a diesel engine that could get more than 40 miles per gallon on the highway. (AP Photo/BMW)

This photo provided by BMW shows the interior of the new BMW 3 Series Gran Turismo, one of two important variations of its popular 3-Series small luxury sports sedans. On Wednesday, March 27, 2013, the German automaker will formally unveil the new 3 Series Gran Turismo, which has a bigger distance between the front and rear wheels to create more rear-seat legroom and cargo space in the trunk. The company also will unveil the 328d in the U.S., a 3-Series equipped with a diesel engine that could get more than 40 miles per gallon on the highway. (AP Photo/BMW)

This photo provided by BMW shows the new BMW 3 Series Gran Turismo, one of two important variations of its popular 3-Series small luxury sports sedans. On Wednesday, March 27, 2013, the German automaker will formally unveil the new 3 Series Gran Turismo, which has a bigger distance between the front and rear wheels to create more rear-seat legroom and cargo space in the trunk. The company also will unveil the 328d in the U.S., a 3-Series equipped with a diesel engine that could get more than 40 miles per gallon on the highway. (AP Photo/BMW)

This photo provided by BMW shows the new BMW 3 Series Gran Turismo, one of two important variations of its popular 3-Series small luxury sports sedans. On Wednesday, March 27, 2013, the German automaker will formally unveil the new 3 Series Gran Turismo, which has a bigger distance between the front and rear wheels to create more rear-seat legroom and cargo space in the trunk. The company also will unveil the 328d in the U.S., a 3-Series equipped with a diesel engine that could get more than 40 miles per gallon on the highway. (AP Photo/BMW)

(AP) ? BMW is giving fans of its 3-Series more room and better gas mileage in two important variations of the small luxury sports sedan that it's rolling out at the New York International Auto Show this week.

On Wednesday, the German automaker will formally unveil a new 3 Series Gran Turismo, which has a bigger distance between the front and rear wheels to create more rear-seat legroom and cargo space in the trunk. The company also will unveil the 328d in the U.S., a 3-Series equipped with a diesel engine that should get more than 40 miles per gallon on the highway.

The 3-Series is the top-selling luxury car in the U.S. BMW sold almost 99,000 3-Series sedans, coupes, and wagons last year, up more than 6 percent from 2011. Luxury automakers overall sold more than 1 million cars in the U.S. last year, an increase of almost 12 percent over 2011.

The Gran Turismo will be available in the fall at U.S. dealers, while the 328d will arrive at showrooms later this year.

Here are the highlights of the two vehicles:

UNDER THE HOOD: The Gran Turismo has the same engines and transmissions as the standard 3-Series: a 2-liter four-cylinder engine or a 3-liter inline 6-cylinder. All-wheel-drive is standard. The 328d will have a four-cylinder turbocharged diesel engine that puts out 180 horsepower. BMW says the car can go from zero to 60 in about 7.2 seconds.

OUTSIDE: The Gran Turismo has a sloped back and tailgate, and is 4.3 inches longer between the front and rear wheels than a standard 3-Series sedan. The 328d looks the same as the standard 3-Series except for a diesel badge.

INSIDE: The 328d's interior will look similar to the standard 3-Series, while the five-passenger Gran Turismo will have a little more back-seat legroom and a trunk that's one cubic foot larger than the regular 3-Series.

GAS MILEAGE: BMW says preliminary estimates show the diesel model gets 45 mpg on the highway. City mileage estimates weren't available. The Gran Turismo should get about what a standard 3-series gets: up to 36 mpg on the highway with a manual transmission and a four-cylinder engine and 33 mpg on the highway with the six cylinder motor and automatic transmission.

PRICE: About $40,000 to start for the diesel. The Gran Turismo 328i starts at just over $42,300. A 320i now starts at just under $33,000, while a 335i begins at just over $45,000.

CHEERS: The 328d brings great gas mileage and performance to the 3-Series, which already was strong in both categories. The Gran Turismo 328i promises a more comfortable ride for passengers on longer trips.

JEERS: The diesel and the Gran Turismo are pricey compared to some of the standard models.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-03-27-Auto%20Show-Hot%20Wheels-BMW%20Diesel%203-Series/id-372aee4699aa4a1eb68bce015f74b622

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মঙ্গলবার, ২৬ মার্চ, ২০১৩

Visual Identity Platform Vizify Launches Out Of Beta, Now Lets You Share Graphics Via Social Media Cards

Screen shot 2013-03-26 at 12.59.04 PMThe Portland-based Vizify came out of TechStars' accelerator in 2011 with the goal of helping everyday people turn their personal data -- the stuff that's fragmented across scores of profiles, networks and websites -- into one, unified visual profile. Essentially, piggybacking on the rise of digital portfolio platforms that aim to recast how we use the resume, Vizify wants to help change how we build our identities online.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/7Q9qvupUWtg/

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Hope for Galapagos wildlife threatened by marine invaders

Mar. 26, 2013 ? Increasing tourism and the spread of marine invasive non-native species is threatening the unique plant and marine life around the Galapagos Islands.

UK scientists from the Universities of Southampton and Dundee are currently investigating the extent of the problem following a grant from the UK Government's Darwin Initiative, which aims to protect biodiversity and promote sustainability around the world.

UK Environment Minister Richard Benyon said: "The UK has played a major role in supporting the establishment of the Galapagos Marine Reserve and our Darwin Initiative has funded a range of important projects protecting and enhancing both marine and terrestrial wildlife.

"Invasive non-native species can cause huge damage to local ecosystems and I am delighted that action is being taken to monitor this threat."

Project leader Dr Ken Collins, Ocean and Earth Science of University of Southampton based at the National Oceanography Centre said: "Tourism is partly to blame for the influx of invasive non-native species, due to the huge rise in ships and planes from mainland Ecuador bringing in pests. In recent years, it was realised that cargo ships were carrying disease-infected mosquitoes, which were attracted to the ship's bright white deck lights. Simply changing from conventional filament bulbs to yellow sodium lamps, along with fumigation in the hold has substantially reduced the threat.

"We are trying to protect marine biodiversity by identifying newly arrived species to the Galapagos, assessing if they have the potential to compete for space and overcome other species of algae and native corals."

White coral, which has already been reported off the mainland Ecuador coast (600 miles away), is also causing anxiety. It could easily hitch a lift on the frequent vessels supplying Galapagos tourists and residents. Already, two new algae species have been found in the Galapagos Marine Reserve, a World Heritage Site.

Another species causing concern and which has the potential to overwhelm natural populations is the Indian Ocean lionfish. This fish colonised the Caribbean through accidental release from an aquarium and has spread through the entire Caribbean in the last decade. Its rapacious appetite has led to the decimation of coral reef fish populations in the southern Caribbean. Lionfish can consume prey up to two thirds of their own length and data shows that they can eat 20 small wrasses in 30 minutes. Their stomachs can expand by up to 30 times in volume when consuming a large catch. The Panama Canal could provide a short cut to Ecuador's Pacific coast and then the Galapagos.

One of Ken Collin's PhD students is Fadilah Ali, who is at the University of Southampton studying how the lionfish is eating its way through coral reef fish populations in the southern Caribbean. For over a hundred years Southampton, one the UK's busiest ports has been receiving marine hitchhikers from around the world, changing the entire balance of its underwater marine plants and animals. One example is the Pacific Oyster, which is being studied in the Solent region by another of Ken's PhD students Steff Deane.

Prof Terry Dawson, SAGES Chair in Global Environmental Change at Dundee, added, "Invasive species are becoming one of the greatest threats to biodiversity on a global scale. The Galapagos islands are particularly vulnerable due to the fact that much of the indigenous wildlife have evolved over millions of years in the absence of predators, competition, pests and diseases, which makes them very susceptible to the negative impacts of aggressive non-native species.

"We are very pleased to have Inti Keith, one of the staff of the Charles Darwin Research Station, registered with the University of Dundee to study for her PhD on this important topic. Her extensive local knowledge of the marine environment of the Galapagos Islands gives us a head start in developing the research to tackle the issue.

The team have recently returned from the Galapagos, where they met the Ecuadorian Navy and DIRNEA, the national maritime authority, to discuss control measures and helped take part in the first underwater survey of the Galapagos capital port.

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The above story is reprinted from materials provided by National Oceanography Centre.

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/x3Tk7129LPw/130326112048.htm

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Researchers unravel molecular roots of Down syndrome

Monday, March 25, 2013

What is it about the extra chromosome inherited in Down syndrome?chromosome 21?that alters brain and body development? Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have new evidence that points to a protein called sorting nexin 27, or SNX27. SNX27 production is inhibited by a molecule encoded on chromosome 21. The study, published March 24 in Nature Medicine, shows that SNX27 is reduced in human Down syndrome brains. The extra copy of chromosome 21 means a person with Down syndrome produces less SNX27 protein, which in turn disrupts brain function. What's more, the researchers showed that restoring SNX27 in Down syndrome mice improves cognitive function and behavior.

"In the brain, SNX27 keeps certain receptors on the cell surface?receptors that are necessary for neurons to fire properly," said Huaxi Xu, Ph.D., professor in Sanford-Burnham's Del E. Webb Neuroscience, Aging and Stem Cell Research Center and senior author of the study. "So, in Down syndrome, we believe lack of SNX27 is at least partly to blame for developmental and cognitive defects."

SNX27's role in brain function

Xu and colleagues started out working with mice that lack one copy of the snx27 gene. They noticed that the mice were mostly normal, but showed some significant defects in learning and memory. So the team dug deeper to determine why SNX27 would have that effect. They found that SNX27 helps keep glutamate receptors on the cell surface in neurons. Neurons need glutamate receptors in order to function correctly. With less SNX27, these mice had fewer active glutamate receptors and thus impaired learning and memory.

SNX27 levels are low in Down syndrome

Then the team got thinking about Down syndrome. The SNX27-deficient mice shared some characteristics with Down syndrome, so they took a look at human brains with the condition. This confirmed the clinical significance of their laboratory findings?humans with Down syndrome have significantly lower levels of SNX27.

Next, Xu and colleagues wondered how Down syndrome and low SNX27 are connected?could the extra chromosome 21 encode something that affects SNX27 levels? They suspected microRNAs, small pieces of genetic material that don't code for protein, but instead influence the production of other genes. It turns out that chromosome 21 encodes one particular microRNA called miR-155. In human Down syndrome brains, the increase in miR-155 levels correlates almost perfectly with the decrease in SNX27.

Xu and his team concluded that, due to the extra chromosome 21 copy, the brains of people with Down syndrome produce extra miR-155, which by indirect means decreases SNX27 levels, in turn decreasing surface glutamate receptors. Through this mechanism, learning, memory, and behavior are impaired.

Restoring SNX27 function rescues Down syndrome mice

If people with Down syndrome simply have too much miR-155 or not enough SNX27, could that be fixed? The team explored this possibility. They used a noninfectious virus as a delivery vehicle to introduce new human SNX27 in the brains of Down syndrome mice.

"Everything goes back to normal after SNX27 treatment. It's amazing?first we see the glutamate receptors come back, then memory deficit is repaired in our Down syndrome mice," said Xin Wang, a graduate student in Xu's lab and first author of the study. "Gene therapy of this sort hasn't really panned out in humans, however. So we're now screening small molecules to look for some that might increase SNX27 production or function in the brain."

###

Sanford-Burnham Medical Research Institute: http://www.burnham-inst.org

Thanks to Sanford-Burnham Medical Research Institute for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127431/Researchers_unravel_molecular_roots_of_Down_syndrome

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Divine purpose in a green valley - Independent Education

To tell the history of Holy Cross School, says Brother Robert James of the Order of the Holy Cross (OHC), ?we need to go back to the arrival of the OHC in South Africa.?

He continues: ?We are an Anglican Benedictine community of monks founded in 1894. Presently we have four monasteries. Our motherhouse is located outside of New York City in West Park, New York, in the US. We also have communities in Santa Barbara, California and Toronto, Canada. At the invitation of Archbishop Desmond Tutu, we began exploring locations for a foundation in South Africa. In 1997, Mariya uMama weThemba (Mary, Mother of Hope) was founded on the grounds of a retreat house, seven kilometres outside of Grahamstown, in the Eastern Cape, run by the Community of the Resurrection of Our Lord. These Anglican sisters were founded in Grahamstown. The intention of the monks was to be a praying Benedictine presence, trusting that the work that needed to be done would be revealed.?

Closure kicked off new classes

It soon was, recalls James, when the school located on a farm adjacent to the monastery was closed by the Eastern Cape Education Department due to a lack of facilities. This left a number of children without access or transport to other schools. The OHC brothers started a transport scheme, but when they discovered the dismal conditions in many township institutions, the Holy Cross Scholarship Fund was started to raise funds to support the education of children at better local schools. ?In addition,? says James, ?an after-school programme, staffed by professional teachers, was started at the monastery in August 2005. Children came directly from school to a small house on our property equipped with two classrooms, two computers and a small kitchen, to be fed, to receive extra help with their homework and to obtain basic skills they needed but had not learned before.?

The attendance showed the brothers that the individual attention the children were receiving meant a concomitant growth in confidence and the ability to learn. ?After six years, we realised that the young pupils deserved a solid foundation phase education and, in 2010, we began Holy Cross School. Having served as the director of the scholarship fund and coordinator of the after-school programme, I was appointed principal of the new venture.?

A no-fee, foundation phase, Xhosa-medium school

The brothers practised patience while it took two years for the school to be registered and built. ?In 2012, we moved into the new school building, catering for a Grade R and Grade 1 class. Our Grade 2 class began in January this year and Grade 3 will be offered in 2014. We are a no-fee, foundation phase, Xhosamedium school, serving rural poor children from the surrounding farms. We transport the children back and forth, as many live more than 10 km away.?

Keeping matters small and simple meant everyone could focus on excellence, says James, explaining that class sizes do not exceed 14. ?We have been blessed to have the services of two dedicated and qualified Rhodes University graduates as our teachers, with an assistant teacher in each class. Our Grade 2 teacher is a former recipient of the scholarship fund and also attended Rhodes University in Grahamstown. Prior to joining us, he had been teaching at Get Ahead School outside of Queenstown for two years. ?We now have three teachers, three assistant teachers, one youth and child care worker, and 42 students.?

Inclusivity, diversity and respect in difficult surroundings James is adept at describing socio-economic conditions in the area. ?Grahamstown is a microcosm of South Africa. BMWs and donkey carts are parked side by side on the High Street. The gap between rich and poor continues to grow here. The majority of the population lives in the outlying townships, where unemployment is extremely high and the conditions in public schools are generally dire. In dramatic contrast, Grahamstown is also the location of some of South Africa?s best independent and private schools in the town itself.?

This part of the vast Eastern Cape is also farming country. Says James: ?The farms surrounding Grahamstown are isolated, and incidences of alcoholism and physical and sexual abuse of women and children are frequent. There is also a high rate of HIV/Aids infection. Because of the complex social issues the children experience in their homes, the school employs a full-time certified youth and child care worker.?

These complex social issues caused the brothers to consider their mission carefully, and their aims and values are clear in their founding statement:

Holy Cross School is an independent Anglican school committed to our Anglican tradition of inclusivity, diversity and respect for all. Our mission is to provide a free, quality foundation phase education to rural children. Our goal is to foster the growth of healthy and integrated children by addressing the needs of their bodies, minds and spirits. Our hope is that this will maximise their potential for future learning and becoming responsible and productive citizens of South Africa.

The commitment to ?fostering the growth of healthy and integrated children? means that hearing, vision and HIV screenings are done regularly at Holy Cross, as well as educational assessments to address any physical or learning challenges. ?School outings to museums and places of interest are also regular features of each term,? adds James.

Immelman invaluable

Like all schools that have joined ISASA in the Eastern Cape, Holy Cross met the organisation?s regional director Jan Immelman shortly after registration and the move into the new building. ?It was the first of a series of meetings as he guided us through the documents required to become members of ISASA,? recounts James. ?The decision to join was instant. Immelman?s advice and expertise was much appreciated, rendering the actual application process painless.?

Advice and support on hand

As Grahamstown is known for its many education institutions, Holy Cross was able to form important relationships with other ISASA schools. ?We have an excellent relationship with St Andrew?s College and the Diocesan School for Girls. The latter has adopted us. They make regular visits and have made Holy Cross the recipient of a number of their fund-raising efforts. Shelley Frayne, the headmistress, was a source of encouragement and practical advice during the registration process.

Paul Edey, the head of St Andrew?s College, serves on our governing board.? Public schools are also important allies for Holy Cross. ?Another member of our board, Madeleine Schoeman, is principal of Ntsike Secondary School. Through her and others, we learn a great deal about local and national efforts to improve public education, as most of our children will be part of the public system in the future,? observes James.

Sensitive social issues

Those of us in urban areas don?t often consider the pitfalls rural schools must face, like poorly maintained roads. Says James: ?Among our challenges are the costs of transport, the toll bad roads take on our vehicles and the long distances we must travel. As much as possible, we try to consolidate the use of our vehicles.?

Social conditions in pupils? home situations are another cause for concern. ?Relationships are often fragile and require sensitive interventions and family conferences. The need for referrals is ongoing. We have cultivated relationships with the Department of Social Services and the South African Police Service. We have also been proactive in offering workshops for parents. We are very proud of the fact that we have established trusting relationships and a safe place for the children to name the situations which threaten them.?

Independence and ISASA services

Much of the important work done by Holy Cross happens because it is an independent school. ?We value our independent status. It allows us greater latitude to promote our holistic approach to education, which best suits the needs of the children who come to us. It also minimises the bureaucracy, which so weighs down the education system in the Eastern Cape,? says James.

Support also comes from ISASA. ?Membership enables us to keep up to date with the legislative and political changes affecting us as independent schools. There is also strength in numbers when advocating for national policy change. Our teachers have benefited greatly by interacting with their colleagues in other member schools, sharing resources and attending training sessions. I attended my first Southern African Heads of Independent Schools Association (SAHISA) meeting in November 2012 and was warmly welcomed.?

Prayer and learning go hand in hand

Driving towards Grahamstown from Port Elizabeth, one will come across the serene valley, home to Holy Cross School and the Mariya uMama weThemba monastery. You may even hear the calming sound of the bells calling the community to prayer. The tranquil vista belies the many hardships faced by those who worship, teach and learn here, but: ?If you came this way, taking any route, starting from anywhere, at any time or at any season?: you would have to put off sense and notion? You are here to kneel where prayer has been valid.?1

Reference:

1. Eliot, T.S. (1968) Four Quartets. New York: Mariner Books.

Source: http://www.ieducation.co.za/divine-purpose-in-a-green-valley-holy-cross-school-joins-isasa/

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